Sitting, and its effects on health, is a hot topic these days. I recently wrote a review of current research, showing how excessive sitting increases our risk of chronic disease and death; it even cancels out the benefits of regular exercise.
It seems like I’m hearing more about this everywhere I turn. The excellent radio show, 99% Invisible, just ran an episode on the health effects of sitting, and how it relates to the history (and future) of chair design. I encourage you to read or listen to this fascinating show.